Diet Tembaga Pengaruh Reproduksi cats1, 2

Dietary Copper Influences Reproduction in Cats

Andrea J. Fascetti
Quinton R. Rogers, dan 
 James G. Morris

 

Abstract

Achieving appropriate growth and nutrient accretion of preterm and low birth weight (LBW) infants is often difficult during hospitalization because of metabolic and gastrointestinal immaturity and other complicating medical conditions. Advances in the care of preterm-LBW infants, including improved nutrition, have reduced mortality rates for these infants from 9.6 to 6.2% from 1983 to 1997. The Food and Drug Administration (FDA) has responsibility for ensuring the safety and nutritional quality of infant formulas based on current scientific knowledge. Consequently, under FDA contract, an ad hoc Expert Panel was convened by the Life Sciences Research Office of the American Society for Nutritional Sciences to make recommendations for the nutrient content of formulas for preterm-LBW infants based on current scientific knowledge and expert opinion. Recommendations were developed from different criteria than that used for recommendations for term infant formula. To ensure nutrient adequacy, the Panel considered intrauterine accretion rate, organ development, factorial estimates of requirements, nutrient interactions and supplemental feeding studies. Consideration was also given to long-term developmental outcome. Some recommendations were based on current use in domestic preterm formula. Included were recommendations for nutrients not required in formula for term infants such as lactose and arginine. Recommendations, examples, and sample calculations were based on a 1000 g preterm infant consuming 120 kcal/kg and 150 mL/d of an 810 kcal/L formula. A summary of recommendations for energy and 45 nutrient components of enteral formulas for preterm-LBW infants are presented. Recommendations for five nutrient:nutrient ratios are also presented. In addition, critical areas for future research on the nutritional requirements specific for preterm-LBW infants are identified. 

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       Tujuan dari penelitian ini adalah untuk menentukan kebutuhan tembaga kucing betina (ratu) untuk kehamilan. Kegiatan Cuproenzyme dievaluasi untuk mengidentifikasi indikator noninvasif status tembaga. Penelitian ini menggunakan model deplesi-hal penuh. Spesifik ratu bebas patogen (n = 28) yang disesuaikan dengan diet murni, setelah mengkonsumsi diet tembaga-deplesi (0,8 mg Cu / kg diet) selama 4 mo, mereka secara acak dialokasikan untuk tiga kelompok pengobatan diet menerima tembaga sulfat pada 4,0 , 5.8 atau 10,8 mg Cu / kg diet. Empat ratu menjalani biopsi hati pada dua titik waktu selama penelitian. Sampel plasma dianalisis untuk konsentrasi tembaga, ekstraseluler superoxide dismutase, ceruloplasmin dan diamina kegiatan oksidase. Konsentrasi tembaga hati hanya responsif terhadap asupan tembaga diet. The diet konsentrasi tembaga memiliki dampak yang signifikan terhadap waktu yang dibutuhkan untuk ratu untuk hamil (P = 0,04). Ada hubungan linear negatif antara tembaga diet (x = Cu mg / kg diet) dan waktu rata-rata (y = hari) untuk ratu untuk hamil (y = 43,38 - 2.87x, R2 = 0,97). Rekomendasi NRC saat ini dari 5 mg / kg diet tembaga untuk kucing muncul marjinal untuk reproduksi optimal.